Prostate adenoma (DGPZ) is also an extremely common disease in men over the age of 40.Through this disease, benign growth of prostate tissue occurs, which can lead to urethra compression and bladder flow out of urine, thus causing unpleasant sensations during urination.Prostate adenomas can also cause serious problems in the bladder and kidneys.

This article discusses the causes and symptoms of prostate adenoma, as well as modern diagnosis and treatment methods.There are many effective treatments for benign prostatic hyperplasia, including not only drug treatment and open surgical intervention, but also minimal invasive surgical treatment.If the first symptom of the disease occurs, you need to consult a doctor who will take into account your symptoms, the size of your hyperplasia, and the general condition of your health and provide you with the best treatment options.
reason
So far, it is not entirely clear which causes prostate increase.However, this may be due to changes in the sex hormone balance in men.During their lifetime, men produce testosterone, androgen and a small amount of estrogen, and female sex hormones.As the body ages, the amount of active testosterone in the blood decreases, while the amount of estrogen remains approximately at the same level.Studies have shown that higher estrogen fractions entering the prostate can increase the activity of substances that accelerate the growth of prostate cells.

Another theory suggests that another male sex hormone - dithyroxine protein - is important for the development and growth of the prostate at a young age.Some studies have shown that even if testosterone levels in the blood begin to drop, high levels of digidrototostosterone are still present in the prostate, which can drive prostate cells to continue to grow.
The prostate is located below the bladder.The urethra (or urethra) that removes urine from the bladder passes through the center of the prostate.It is precisely because of this anatomy that an increase in the prostate can prevent urine from flowing.
Risk factors that increase the prostate may be:
- age.In men under the age of 40, symptoms of prostate increase are rarely observed.About 30% of men experience moderate symptoms over 60 years, about 50% - to 80 years.
- The existence of DGPZ among relatives.For example, if your blood relative has a father or brother who has a prostate problem, then this also means you can also increase the risk of prostate hyperplasia.
- Other diseases such as diabetes, cardiovascular disease and erectile dysfunction.Research shows that in some cases, diabetes, erectile dysfunction, as well as heart disease and blood vessels may increase the risk of DGPZ.
- Life.Obesity increases the risk of DGPZ, and physical exercise can reduce this risk.
However, the existence of any of the above factors is not the basis of believing that you will definitely develop into a prostate adenoma.
symptom
Patients with prostate adenoma have different symptoms.
General signs and symptoms of DGPZH include:
- A desire to urinate frequently or urgently.
- Nocturnal urination (Nokturia).
- Can't be completely empty.bladder.
- The presence of urine remaining in the bladder.
- The urine stops periodically during urination.
- Complexity of the onset of urination.
- The growth of urine at the end of urination.
- Frequent urinary tract infections.
- Urination is completely impossible (Anuria).
- The presence of blood in the urine (hematuria).
It is worth knowing that the size of the prostate does not necessarily determine the severity of your symptoms.Some men with slightly enlarged prostate may experience severe symptoms, while others may experience extremely severe symptoms.Almost all patients' characteristics gradually worsen with symptoms over time.It is extremely rare that symptoms can stabilize or even improve over time.
diagnosis
If DGPZ is suspected, your doctor will ask detailed questions about the symptoms of the disease and will undergo a physical examination.This initial phase may include:
- A survey to identify symptoms and risk factors of the disease.
- Finger rectal examination.To assess the size and shape of the prostate, the doctor needs to insert his finger into the rectum.This study is very useful and allows you to draw major conclusions about prostate status.
- Urine analysis.Analysis of urine samples can help eliminate infections or other diseases that may cause similar symptoms.
- blood test.The results of blood tests may indicate the availability of kidney problems.
- Blood test of prostate-specific antigen (PSA).This dog is a protein produced only from prostate fabrics.When the current state is healthy, few dogs are found in the blood.The test can be performed in a laboratory, a hospital or a doctor's office.No special training is required.Rapid increase in dog levels may indicate rapid growth of prostate fabrics.DGPZH is one of the possible reasons for high levels of PSA.Inflammation of prostatitis or prostatitis is another common cause of high levels in dogs.
After performing a preliminary examination and performing the necessary examination, your doctor may recommend additional studies to confirm the presence of DVGPH and rule out other conditions.These tests may include:
- Urine dynamics test.In this study, patients were urinated in a container connected to a special device that measured the intensity and volume of the stream during urination.Test results help track the development of the disease and determine whether your condition will get better.
- Test the residual volume of urine.This test shows if you can completely empty your bladder.Tests can be performed using ultrasound studies or by introducing a catheter into the bladder after helping to measure how much urine is left in the bladder.
- Keep a urination diary for 24 hours.Registration of urination and urine volume may be especially useful if more than one-third of your daily urination occurs at night.
- Transrectal ultrasound.Meanwhile, UZ-Zond is introduced into the rectum to measure size and evaluate prostate status.
- Bladder study (cystoscopy).In this study, a flexible catheter (cystoscopy) with the end of the camera was inserted into the urethra, allowing doctors to see the urethra and the inner surface of the bladder.
- Prostate biopsy.It may be necessary to take prostate tissue samples to rule out prostate cancer.
treat
There are many different treatment options for prostate adenoma.You and your doctor must decide which treatment is best for you.Sometimes, a combination of various programs is most effective.Cases of mild DHCH may not require treatment.
The main treatments for prostate adenoma are:
- Actively observe the disease.
- Drug therapy.
- Small invasive surgery.
- Surgical intervention measures.
- Take the initiative to observe.
If your doctor prefers this option, your disease will be carefully monitored without using any medication or surgical procedures.At the same time, you will check you every year.If your symptoms worsen or new symptoms appear, your doctor may provide you with active treatment.Men with mild symptoms can be good candidates for positive observation.Men who do not bother with their moderate symptoms are also good candidates.
The advantage of this method is that it has no side effects, but it is difficult to relieve symptoms.
Medical Therapy
Alpha blockers
Alpha blockers are drugs that relax the urethra, prostate, and bladder muscles.They can improve urine outflow and relieve symptoms of DHCH without affecting the size of the prostate.Alpha blockers include afusoside, terazozin, doxazosin and tamsulosin.
One of the advantages of Alpha blockers is that they start working immediately after admission.Side effects may include dizziness, fatigue, and ejaculation problems.
Men who have moderate to severe DGPZ and worry about symptoms are good candidates to start using alpha blockers.
5-α reductase inhibitor
5-α reductase inhibitors are drugs that block the production of dihydrotestosterone (androgen) and can accumulate in the prostate and cause its growth.These drugs cause a decrease in prostate size and increase urine outflow.Such drugs include Finatoride and Dutasteride.
These drugs greatly reduce the risk of DHCH complications.They also reduce the possibility of future operations.Side effects include erectile dysfunction and decreased libido (sexual desire).At the same time, you will have to continue taking tablets to prevent the recurrence of symptoms of the disease.
Combination Therapy
In combination therapy, alpha blockers and inhibitors of 5-α reductase were used together.Possible combinations of drugs include Finsteride and Duxasosine or Dutastastilide and Tamsulosin.If you have symptoms of ADHD, your urologist can also prescribe a combination of alpha-blockers for alpha-blockers.The bladder is overactive, and the bladder muscles are uncontrolled, resulting in increased urination frequency and sudden desire for emergency urine and incontinence.Anti-mucus protein drugs are drugs that relax the bladder muscles.
Combination treatment can significantly improve symptoms and prevent worsening of DHGPH status.However, it is worth remembering that each drug can cause side effects.Taking two medications, you may have more side effects than taking only one medication.
Alternative treatment
It is not recommended to use various herbs (herbs) to self-determination, use traditional medicine or treatment.Many studies have shown that the use of this treatment is ineffective and in some cases irreparable harm can be brought.In addition, the testing process for herbs and bioactive food additives (dietary supplements) does not have the same testing process as the drug.As a result, the quality and cleanliness of additives without recipes may vary.
Small surgical interventions
The least invasive intervention is performed with minimal anesthesia and a faster recovery is recommended.Typically, the procedure can be performed in the doctor's office or outpatient center.
Immediate relief of the symptoms of the disease is the greatest advantage of minimally invasive surgery.In many men, urine outflow and bladder function control were improved after minimal invasive intervention.If you have problems urinating, obstruction of the urinary tract, stones in the bladder, blood in the urine, the amount of urine remaining in the bladder after emptying, or you have not noticed the effects of taking medication, then minimally invasive interventions may be the next step in the treatment of the disease.
However, any surgical intervention worth knowing, including minimally invasive interventions, have risks of side effects, including:
- Urinary tract infection.
- Blood in urine.
- Burn during urination.
- Need to empty the bladder more frequently.
- Sudden urination.
- Erectile dysfunction.
Methods of minimally invasive surgery include:
- Elevation of the prostate urethra (or pulse method) - Using this process, a special device is used to install tiny implants in the prostate.These implants are elevated above and maintain the swollen prostate at this location, while the pressure in the urethra is reduced and urine outflow is improved.In this case, no tissue that destroys or removes prostate tissue will occur.PUL can be performed by local and general anesthesia.Most patients noticed improvements in symptoms within 2 weeks.In some cases, pain or burning pain occurs in urine, blood in urine, or a strong desire to urinate.Often these side effects occur within two to four weeks.A good candidate who expresses elevated prostate urethra can be a patient with a high risk of having other medical problems or surgical interventions.
- Transurethral Microwave Therapy (or TUMT method) - Use microwaves during this process to destroy prostate tissue.First, the doctor introduced the catheter to the prostate through the urethra, and then sent the microwave built into the catheter to the part of the heated prostate.High temperatures can destroy too much prostate fabric.Through this process, anesthesia is usually not required and the risk of side effects is minimal.
- Methods for treating prostate pathology using water vapor (Rezum Therapy) convection ablation - This process uses heat to destroy excess prostate tissue.In this case, the sterile water in a special portable device is heated to a temperature above the boiling point that becomes steam.This hot steam then causes the cells to die quickly.Treatment can be performed in the doctor's office under local anesthesia.After the surgery, you may have a period of blood mixing in your urine and you will need to use the catheter for a few more days.Pain or frequent urination after surgery should pass after about 3 weeks.Sexual side effects, such as erectile dysfunction, are unlikely.
Traditional surgical procedures
By removing some surgical interventions in part of the prostate tissue, other treatments are ineffective and have extremely high symptoms (e.g., it is completely impossible to urinate).These include:
- Clear prostatectomy (TURP)
TURP is one of the most common operations in DHC.During this surgery, after anesthesia, the surgeon introduced a special thin tool through the penis head to the urethra.Using this tool, your doctor removes excessive tissue from the prostate.After surgery, it is usually necessary to use the catheter for 1-2 days.The effects of this treatment usually last for 15 years or more.Like any other procedure, TURP has side effects, and the anesthesia used in the intervention is related to certain risks.Side effects of TURP may include retrograde ejaculation, erectile dysfunction, postoperative urinary tract infections, and urinary incontinence.Complete recovery takes 4 to 6 weeks.
- Laser shell of the prostate
With this intervention, the surgeon passes thin tools through the penis in the urethra.The laser inserted into the tool destroys the excess prostate fabric.Meanwhile, like urethralectomy of the prostate, no cutting is required.The recovery after laser removal is very fast, but after a few days you may get blood in your urine and urinate frequently or painfully.Through this process, anesthesia is also required, which is related to certain risks.
- Prostate clearance operation
Currently, among the ineffectiveness of all other treatments, the removal of the prostate during DGPZ is extremely rare.Such operations are associated with significant risks and side effects, including urination, invasion of erectile function, and serious complications of the operation itself.
complication
Lack of timely medical services in DGPG can lead to the development of serious complications, including:
- Suddenly and completely unable to urinate (urinary delay, Anuria).In this state, it may be necessary to enter the catheter into the bladder to provide urine outflow from the crowded bladder.In some cases, surgery may also be required to reduce urinary retention flexion.
- Urinary tract infection.Inability to completely empty the bladder can increase the risk of urinary tract infection.
- Bladder stone.Since it is impossible to completely empty the bladder, stones in the bladder are also formed.Stones can cause the development of infection, bladder irritation, blood impurities in the urine, and further difficulties in the outflow of urine.
- Damage to the bladder.Due to incomplete emptying, the bladder can be stretched, and over time, the bladder can cause its muscle wall to weaken.As a result, the bladder fails to compress properly, which is the reason for further difficulty in emptying.
- Kidney damage.Delayed urine can lead to increased bladder pressure and reverse outflow of urine to the kidneys, resulting in direct damage or increased risk of infectious diseases.Such complications are very serious and can be preserved for life.
The development of these complications is extremely rare in most men with increased prostate, but it must be remembered that many complications, including acute urinary retention or kidney damage, can pose a serious threat to your health and life.If any symptoms of the disease occur, consult your doctor immediately.
Diet and prevent the development of prostate adenoma
Unfortunately, there is no reliable way to prevent the development of prostate adenomas, but the rate of prostate increase can reduce weight loss and proper nutrition, while the diet is high in fruit and vegetables.This may be due to the fact that excessive fatty tissue in the body can increase levels of hormones and other blood factors and stimulate the growth of prostate cells.Continuous physical exercise also helps control hormone weight and levels, thereby reducing the risk of developing prostate adenomas.